A 45-year-old man comes to the office due to slowly progressive back and joint pain; his knees and ankles are stiff and painful when he walks. Over the past year he has had excessive sweating, and his ring and shoe sizes have increased. Physical examination shows coarse facial features with a prominent forehead, protruding jaw, and widely separated maxillary teeth, plus mild swelling and crepitus of the knees and ankles. Which of the following is most likely to be associated with this patient's condition?
Select any text to highlight it or add a note — your annotations stay with the question.
Select an answer to reveal the correct choice and explanation.Tip: press A–E to answer.